Laboratory test early detection preeclampsia

The Dianeonatal ELISA (Enzyme Linked Immunosorbent Assay) [DN-E2] is a diagnostic device for the specific and early detection of a stroke.
The ELISA is a quantitative detection method for the enzyme glycogen phosphorylase isoenzyme BB (GPBB). This early marker can be an important indicator of preeclampsia for the doctor.
The Dianeonatal® ELISA (laboratory test) enables the quantitative detection of the enzyme GPBB, which is released into the blood by ischemic placental tissue. Noticeably increased GPBB levels in the blood that occur shortly after the first typical symptoms are evidence of preeclampsia.
Sandwich ELISA, 96-well microtiter plates, compatible with commercially available ELISA readers.
Planned in the near future.

The Dianeonatal ELISA laboratory test system is manufactured by an ISO-certified contract manufacturer.


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The enzyme GPBB enters the bloodstream when ischemia, i.e. an oxygen undersupply of the heart, brain or placenta, occurs.
In pregnant women, an increased levels of GPBB can generally be detected in the blood, as your body has an increased oxygen consumption. However, if preeclampsia is present, a significant increase in GPBB can be measured. Preeclampsia is a widespread pregnancy complication characterized by high blood pressure and proteinuria, which, if left untreated, can lead to death.


The detection of an increased level of GPBB in the blood of pregnant women can therefore indicate the presence of preeclampsia at an early stage and ensure that treatment and monitoring of the patients can be started in good time, so that the pregnancy can proceed without further problems.

The DIANEONATAL® ELISA quantitatively shows GPBB, which is released from ischemic placental cells into the bloodstream. Exceptionally elevated GPBB levels in the blood shortly after the first occurrence of typical symptoms therefore indicate the presence of preeclampsia.


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